NFL Football Picks

The San Francisco 49ers got their pieces back and have been destroying opponents ever since. They’ll head north to the Emerald City to take on Geno Smith and the Seattle Seahawks as -7 road favorites in the third and final game of Thanksgiving Day. Read Loot’s game preview and get his SF/Sea pick here!

While Americans across the country devour turkey, mashed potatoes, gravy, stuffing and other tasty eats, the Dallas Cowboys will be feasting on the porous Washington Commander’s defense! Oddsmakers have installed the Pokes as heavy -10.5 favorites. Get Jay’s Wash/Dal prediction here!

In a matchup with major divisional playoff implications, the 11-3 New England Patriots host the 10-4 Buffalo Bills for a Saturday afternoon showdown at Gillette Stadium in Foxboro. The Patriots have dominated the series since 2001, going 33-3 in their last 36 meetings including a 16-2 mark at home.

Expect fireworks in this Week 16 NFL matchup as neither secondary is likely to be able to stop the opposing offense. The Tampa Bay Buccaneers are still a live dog despite injuries to their two top wide receivers as the Texans defense has been very poor since the departure of J.J. Watt.

We were a bit surprised to see the Colts open as +9 underdogs against the Saints defense, who got ripped apart by the Niners last week. It’s especially interesting seeing as though the Colts have only lost once by more than nine points this season. Keith’s calling for a shootout! See who he’s betting in this Week 15 thriller!

The San Francisco 49ers pulled off an exciting in last week at New Orleans. They’re getting a bit much love from oddsmakers here though, as they’re currently sitting at -11 vs. the Atlanta Falcons, who have also been playing decent. Can the Dirty Birds stay warm at the betting windows or will SF continue to impose their will at home where they’re won twelve of the last fourteen in SF vs. Atlanta?

Things change during the NFL season. At one point just a few short weeks ago, the Cowboys were surging and the Rams were sinking. Now in Week 15, the scenario is just the opposite. The +3 point spread here tells us all we need to know.

Something has to give! Both of these teams have played stellar against NFC North foes as the Bears are 9-2 ATS in their last eleven and the Packers have covered their last 6 vs. division opponents. Oddsmakers have these teams valued nearly evenly, with the Lambeau home field advantage bumping the line to -4.5 in favor of GB. This game will likely play out closer than most think.

The Minnesota Vikings are in a “false favorite” situation here. With an overall record of 9-4 straight up and 7-6 against the spread, they find themselves in a real bad spot in Week 15 against a Los Angeles Chargers team that they don’t match up with very well. Kirk Cousins is horrible when pressured and he’ll get all he can handle from Bosa and Ingram. The Bolts are a live dog here!

Week 15 will show us what the Patriots are made of. After back to back losses and the end of their home winning streak, they get a creampuff road matchup vs. the Cincinnati Bengals, or is it? Bill Belichick is known for taking away the opponents best weapon. Cincinnati really only has one, so in theory, the Pats should be able to bang out a win here.