St. Louis Cardinals vs Atlanta Braves Betting Preview | April 21, 2025

St. Louis Cardinals vs. Atlanta Braves
Date: Monday, April 21st, 7:15 ET
Location: Truist Park
TV: None
Money Line: Cardinals +158/Braves -187
Total Line: 8.5

Note: You’re overpaying for odds if you’re not betting at reduced juice!

Betting Preview

Here’s our betting preview for the upcoming MLB clash between the Atlanta Braves and the Cardinals on Monday, April 21st at Truist Park. We provide you with a comprehensive analysis, odds, and predictions to help with your handicapping decision or tail our expert based on the projected lineups and listed starting pitchers.

Betting Odds

From Truist Park in Atlanta, we have the Cardinals and Braves facing off in an NL matchup. First pitch for this one is set for 7:15 PM ET, and the forecast calls for broken clouds and temperatures in the low 80s.

St. Louis is 9-13 and they will be looking to end a four-game losing streak. The Braves are favored on the money line, with their odds sitting at -187, and they have won three straight. In the NL Central, the Cardinals are 4th, while the Braves are 5th in the NL East.

Cardinals vs. Braves Projected Lineup

Straight Up/Over-Under/ Runline Record

St. Louis Cardinals: 9-13 SU / OU 12-9 / Runline 9-13
Atlanta Braves: 8-13 SU / OU 9-9 / Runline 8-13

Cardinals Records & Recent Play

The Cardinals will be looking to get back on track after closing out their series vs. the Mets with a 7-4 loss. This was especially tough, as they held a lead going into the 7th inning before the Mets scored three runs in the bottom of the 7th. St. Louis was the +122 underdog on the money line going into the game.

Sonny Gray put together a good start for the Cardinals, going six innings giving up just three earned runs, and striking out six. However, the Cardinals couldnjson’t close things out, and JoJo Romero took the loss out of the bullpen. The Cardinals also wasted a big game from Willson Contreras, who went 2/4 with a run scored.

St. Louis is 4th in the NL Central, trailing the Cubs by four games with a record of 9-13. The Cardinals are on a four-game losing streak, dropping their final game of the series vs. the Mets, and have lost the first three games of this streak to the Braves. So far, they are 1-2 in the division.

At home, the Cardinals have gone 8-4 this year, but they have really struggled on the road at 1-9. As the underdog, the Cardinals are 9-13 this year, and they have lost four straight as the underdog. St. Louis’ overall series record is 3-4, and they were swept by the Mets in their most recent series.

Braves Records & Recent Play

Heading into their last game vs. the Twins, the Braves closed out the series with a 6-2 win. Leading up to the game, they were the slight favorite at -115 on the money line. It was a big 1st inning for the Braves, as they scored two runs and added another two runs in the 3rd.

Grant Holmes put together a good start for the Braves, going 5 2/3 innings and giving up just one run on four hits. He only had one strikeout in the outing and got the win.

Atlanta is 5th in the NL East, trailing the Mets by 6.5 games. Overall, the Braves are 8-13 and have won three straight games, with their winning streak coming at the end of their series vs. the Twins. So far, they are 3-2 in divisional games.

At home, the Braves have gone 6-2 this year, but they have really struggled on the road, going 2-11. So far, they have yet to play a game as the favorite. As for their overall series record, the Braves are 2-4-1 this year.

Pitching Matchup

Erick Fedde and the Cardinals are on the road against the Braves today. Fedde has started three games this season, and he has a 1-2 record. His last time out, he took the loss vs. the Astros, but he did strike out five batters in 6 innings. On the year, he has 11 strikeouts in 15 innings pitched.

Spencer Schwellenbach is getting the start for the Braves at home against the Cardinals. He has made 3 starts so far this season and has a win and a loss to his name. In his last outing, he took the loss against the Blue Jays, giving up six runs in 4 2/3 innings. However, in his first start of the year, he was dominant, going eight innings and striking out 10 Marlins hitters.

Cardinals vs. Braves Offense Outlook

St. Louis comes into today’s game with the league’s 2nd best team batting average at .262, and they have been even better at home, averaging 5.3 runs per game. Overall, they are 7th in the league at 4.7 runs per contest. The Cardinals are also near the top of the league in on-base percentage, slugging percentage, and OPS.

Over his last seven games, Brendan Donovan has gone 10/27 with one home run and three RBIs. This has helped him move his season batting average up to .356, which is 3rd best on the team. Iván Herrera has also been a big part of the Cardinals’ offense this season, as he is hitting .381 with a team-high four homers.

So far this season, the Braves are averaging 3.7 runs per game, which is 23rd in the league. However, they have been much better at home, averaging five runs per contest. As a team, they are batting .230, which is 15th in the league, and have the 8th most home runs in the league. Austin Riley has been hot of late, going 3/7 with three homers in his last seven games, and is batting .264 for the season.

Currently, Matt Olson is on a five-game hitting streak and is 3rd on the team with 13 RBIs. For the season, Olson is batting just .233, but he does have three homers. Marcell Ozuna is also tied for 2nd on the team with four homers and is batting .305.

Free Cardinals vs. Braves MLB Pick

The Cardinals are really struggling of late, having lost four straight, and the Braves are the heavy favorite. However, I think Erick Fedde helps get the Cards back on track tonight, and I think St. Louis pulls off the upset. I like St. Louis on the money line.

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