Cubs vs. Padres Prediction: High-Scoring Affair at PETCO Park?

by | Last updated Apr 14, 2025 | mlb

Chicago Cubs vs. San Diego Padres
Date: Monday, April 14th, 9:40 ET
Location: PETCO Park
TV: MARQ
Money Line: Cubs +136/Padres -161
Total Line: 7.5

Betting Preview

Here’s our betting preview for the upcoming MLB clash between the San Diego Padres and the Cubs on Monday, April 14th at PETCO Park. We provide you with a comprehensive analysis, odds, and predictions to help with your handicapping decision or tail our expert based on the projected lineups and listed starting pitchers.

Betting Odds

ML RL Total
CHC +136 +1.5 O 7.5 (-103)
SD -161 -1.5 U 7.5 (-118)

The forecast for Monday’s Cubs vs. Padres game calls for cloudy skies and temperatures in the mid-60s. The game will get started at 9:40 PM ET from PETCO Park in San Diego, and the Cubs are 11-7 compared to the Padres at 13-3.Chicago has won two straight, while the Padres are on a four-game winning streak. Dylan Cease will start for the White Sox, and the Cubs are the slight money line favorites at +136. The Padres are -161 at home. This game is being televised on MARQ.

Cubs vs. Padres Projected Lineup

Player Batting Order Position
Ian Happ 1 LF
Kyle Tucker 2 RF
Seiya Suzuki 3 DH
Michael Busch 4 1B
Dansby Swanson 5 SS
Nico Hoerner 6 2B
Pete Crow-Armstrong 7 CF
Matt Shaw 8 3B
Miguel Amaya 9 C
Jameson Taillon SP


Player Batting Order Position
Fernando Tatis Jr. 1 RF
Luis Arraez 2 1B
Manny Machado 3 3B
Gavin Sheets 4 DH
Xander Bogaerts 5 SS
Jose Iglesias 6 2B
Jason Heyward 7 LF
Brandon Lockridge 8 CF
Elias Díaz 9 C
Dylan Cease SP

Straight Up/Over-Under/ Runline Record

Chicago Cubs: 11-7 SU / OU 12-5 / Runline 11-7
San Diego Padres: 13-3 SU / OU 7-8 / Runline 13-3

Cubs Records & Recent Play

Pete Crow-Armstrong had a big game at the plate in the Cubs’ 4-2 win over the Dodgers to close out their series. The Cubs were the heavy underdog at +195 going into this matchup. Crow-Armstrong went 3/4 with two homers and two RBIs. The Cubs really got things going with a three-run 2nd inning and added another run in the 3rd.

Colin Rea got the start for the Cubs, going 3 2/3 innings and giving up just one run. He also issued only one walk and struck out five Dodgers batters. Ethan Roberts picked up the win out of the bullpen, and Ryan Pressly got the save.

Chicago is 11-7 overall this season, and they lead the NL Central by two games over the Reds. The Cubs are just getting started in divisional play, and they are currently on a two-game winning streak. The Cubs have won two straight as the underdog, and they are 7-3 as the road underdog this season.

So far, the Cubs are 4-4 at home and have gone 7-3 on the road. Chicago has won four straight series, and they are 4-1-1 in series matchups this year. Their overall record in their last ten games is 7-3.

Padres Records & Recent Play

Heading into their last game vs. the Rockies, the Padres closed out the series with a 6-0 win. Leading up to the game, they were the heavy favorite at -244. It was a four-run 1st inning that really turned things in their favor, and the Rockies could only score two hits. San Diego’s offense added another two runs in the 4th to put things out of reach. Going into the game, the Padres were ‘the only team in the league without a home run.

Michael King put together a good start for the Padres, going nine innings and not giving up a run. He also issued just one walk and struck out eight Rockies batters. San Diego’s offense was carried by Jose Iglesias, who went 2/2 with two doubles, a run scored, and two RBIs.

San Diego is hosting the Cubs today with an overall record of 13-3, and they have won four straight games. The Padres lead the NL West by 1.5 games over the Giants and are a perfect 10-0 at home this season. So far, they have yet to lose a game to another team in the NL West.

As for how they have fared as the underdog, the Padres have been perfect this season at 13-3. They also have a ten-game winning streak at home right now, and they closed out their series vs. the Rockies with three straight wins. Currently, their overall series record is 4-1.

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Pitching Matchup

Jameson Taillon and the Cubs are on the road to take on the Padres today. Taillon has started all of his games on the road so far this season, and he is coming off a win over the Athletics in his last outing. He went six innings in that game, giving up two earned runs and striking out 7. Taillon’s first start of the year was a loss to the Diamondbacks, where he went 4 1/3 innings and gave up six hits and six runs.

Dylan Cease is getting the start for the Padres at home against the Cubs. Cease has started two games this season, picking up a win in his first outing and then taking the loss in his last start. In that loss, he gave up nine runs in 4 innings of work.

Cubs vs. Padres Offense Outlook

Chicago’s offense has been the best in the league this season, averaging 6.4 runs per game. They have been even better on the road, averaging 7.6 runs per contest. The Cubs are also one of the top home run-hitting teams in the league and have the league’s top on-base percentage.

Carson Kelly has been the Cubs’ best hitter so far, batting .417 with three homers. He has also gone 3/6 in his last three games with two homers. Kyle Tucker is also swinging a hot bat, hitting .324 for the season, and is on a three-game hitting streak.

San Diego comes into the game as the league’s top-hitting team, with a team batting average of .283. They are also one of the top home run-hitting teams in the league and have the best slugging percentage in the league. Overall, the Padres are averaging 4.6 runs per game, which is 10th in the league. At home, they are averaging 5.2 runs per contest.

Fernando Tatis Jr. and Jackson Merrill have been two of the Padres’ top hitters this season, with Merrill leading the team with a batting average of .378, and Tatis Jr. is right behind him at .351. Tatis Jr. has three homers in his last six games and is on a three-game hitting streak.

Free Cubs vs. Padres MLB Pick

For tonight’s Cubs vs Padres matchup, I’,m looking at this over/under line sitting at 7.5, and am jumping on the over. I think the Padres will get to Jameson Taillon early, and the Cubs’ offense is good enough to help push this game past 7.5 runs. Look for a higher-scoring game than expected in San Diego tonight.

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